洋書

<ウィリアムズ血液学,第9版>

Williams Hematology, 9th ed.

著者 : K.Kaushansky, M.A.Lichtman, J.T.Prchal, et al.(eds.)
出版社 : MCGRAW-HILL COMPANIES
ISBN : 978-0-07-183300-4
ページ数 : 2505pp.
出版年 : 2016年

在庫あり

定価58,579円(本体54,240円 + 税)

  • 商品説明
  • 主要目次

血液疾患の構造と臨床管理において世界中でもっとも高評価を受けたリファレンス
本書は何年にもわたり版を重ね,血液細胞および凝固蛋白の良性・悪性疾患の発生,病態生理学的機序,管理に関する知識を,さまざまな領域の医師・研究者らに与えてきた.編集は研究・臨床で名を馳せた専門家,執筆は各領域で有名な専門家によって行われており,血液学テキストの代表的存在として世界的に認められている.患者評価から始まり,正常・異常血液の分子,細胞に関する知識の基礎固めへと進む.続いて,赤血球,顆粒球・単球,リンパ球・形質細胞の異常,骨髄系・リンパ系悪性腫瘍,止血と血栓,輸血医学などを取り上げる.

【本書の特色】
・基礎科学,応用病態生理学,臨床における最新の進歩を反映
・章を刷新し,写真700点(うち300点は新たに追加),イラスト475点をカラーで掲載
・診断における血液細胞・骨髄細胞形態の重要性から,関連疾患のカラー画像を各章にまとめた

Table of contents

1. Initial approach to the patient: History and physical examination
2. Examination of blood cells
3. Examination of the marrow
4. Consultative Hematology
5. Structure of the marrow and hematopoietic microenvironment
6. The organization and structure of lymphoid tissues
7. Hematology of the fetus and newborn
8. Hematology during pregnancy
9. Hematology in older persons
10. Genetic principles
11. Genomics
12. Epigenetics
13. Cytogenetic and Genetic Abnormalities
14. Metabolism of Hematological Neoplastic Cells
15. Apoptosis and Autophagy
16. Cell cycle regulation and hematological disorders
17. Signal transduction pathways
18. Hematopoietic stem cells, progenitors, and cytokines
19. The inflammatory response
20. Innate immunity
21. Adaptive immunity
22. Pharmacology and toxicity of antineoplastic drugs
23. Hematopoietic stem cell transplantation
24. Treatment of infections in the immunocompromised host
25. Antithrombotic therapy
26. Immune cell therapy
27. Vaccine therapy
28. Therapeutic apheresis: indications, efficacy, and complications
29. Gene transfer for therapy
30. Regenerative Medicine: Multipotential cell therapy for tissue replacement
31. Structure and Composition of the Erythrocyte
32. Erythropoiesis
33. Erythrocytes turnover
34. Clinical manifestations and classification of erythrocyte disorders
35. Aplastic anemia
36. Pure red cell aplasia
37. Anemia of chronic disease
38. Erythropoietic effects of endocrine disorders
39. The congenital dyserythropoietic anemias
40. Paroxysmal nocturnal hemoglobinuria
41. Folate, cobalamin and megaloblastic anemias
42. Iron Metabolism
43. Iron deficiency and overload
44. Anemia resulting from other nutritional deficiencies
45. Anemia associated with marrow infiltration
46. Erythrocyte Membrane Disorders
47. Erythrocyte Enzyme Disorders
48. The thalassemias
49. Disorders of hemoglobin structure: sickle cell anemia and related abnormalities
50. Methemoglobinemia and other dyshemoglobinemias
51. Fragmentation hemolytic anemia
52. Erythrocyte disorders as a result of chemical and physical agents
53. Hemolytic anemia due to infections with microorganisms
54. Immune Hemolytic Anemia
55. Alloimmune hemolytic disease of the fetus and newborn
56. Hypersplenism and hyposplenism
57. Primary and Secondary Polycythemias
58. The porphyrias
59. Hereditary and acquired (polyclonal) sideroblastic anemias
60. Structure and composition of neutrophils, eosinophils, and basophils
61. Production, distribution, and fate of neutrophils
62. Eosinophils and their disorders
63. Basophils and mast cells, and their disorders
64. Classification and clinical manifestations of neutrophil disorders
65. Neutropenia and neutrophilia
66. Disorders of neutrophil function
67. Structure, biochemistry, and function of monocytes and macrophages
68. Production, distribution, and fate of monocytes and macrophages
69. Classification and clinical manifestations of disorders of monocytes and macrophages
70. Monocytosis and monocytopenia
71. Inflammatory and malignant histiocytosis
72. Gaucher Disease and Related Lysosomal Storage Diseases
73. Structure, composition, and biochemistry of lymphocytes and plasma cells
74. Lymphopoiesis
75. Functions of B lymphocytes and plasma cells in immunoglobin production
76. Functions of T lymphocytes: T-cell receptors for antigen
77. Functions of natural killer cells
78. Classification and clinical manifestations of lymphocyte and plasma cell disorders
79. Lymphocytosis and lymphocytopenia
80. Immunodeficiency diseases
81. Hematological manifestations of acquired immunodeficiency syndrome (AIDS)
82. Mononucleosis syndromes
83. Classification and clinical manifestations of the clonal myeloid disorders
84. Polycythemia vera
85. Essential thrombocythemia
86. Primary myelofibrosis
87. Myelodysplastic disorders (Clonal cytopenias and oligoblastic leukemia)

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